Control primates were housed in individual cages without their movements being restricted.Total body fluid (TBF), intracellular fluid volume (IFV) and circulating plasma volume (CPV) decreased significantly (p < 0.05), while extracellular fluid volume (EFV) and interstitial fluid volume (IsFV) decreased significantly (p < 0.05) at the initial seven days of the HK period and after the 7th day increase progressively in HKP compared with their pre-HK values and their respective control values in VCP. Hypokinetic primates were kept for 90 days in small individual cages that restricted their movements in all directions without hindering food and fluid intakes. All primates were divided equally into two groups: vivarium control primates (VCP) and hypokinetic primates (HKP). Understanding of fluid transfer between body fluid compartments and its regulating mechanisms was the aim of this study for disclosing impaired fluid retention during hypokinesia (HK).Studies were done on 12 male Macaca mulatta (rhesus monkeys) aged three to five years (5.15 to 6.56 kg) during 90 days period of pre-HK and 90 days period of HK. Zorbas, Yan Kakurin, Vassilly Denograndov, Sergei Yarullin, Vladimir Tsiamis, KostasД«ody fluid homeostasis undergoes significant changes during hypokinesia (diminished movement).

Fluid distribution measurement between body compartments in primates in disclosing fluid retention during prolonged hypokinesia Fluid distribution measurement between body compartments in primates in disclosing fluid.

Measuring body fluid compartments